Wendy Blanda,Jonathon Daryll Holt,Andrew Nathan Brimer,Karl Malcolm,Clare McCoy,Diarmaid Murphy,Peter John James Boyd
申请号：
US15519280
公开号：
US20170224823A1
申请日:
2015.10.22
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides intravaginal drug delivery devices, such as intravaginal rings, comprising active pharmaceutical ingredients (APIs) having terminal alkene, alkyne or carbonyl functionalities. The devices of the invention exhibit increased recovery of the active pharmaceutical ingredient from platinum-catalyzed silicone polymers due to the optimization of drug particle size and cure conditions. The present invention also provides methods of preventing unintended pregnancy in a female human, methods of preventing unintended pregnancy in a female human and HIV infection in a female human, and methods of preparing intravaginal drug delivery devices.
