JAKOBSEN, BENT KARSTEN,ANDERSEN, TORBEN BENT,MOLLOY, PETER EAMON,LI, YI,BOULTER, JONATHAN MICHAEL
申请号：
CA2505558
公开号：
CA2505558C
申请日:
2003.10.30
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
A proteinaceous particle, for example a bacteriophage, ribosome or cell,displaying on its surface a T-cell receptor (TCR). The displayed TCR ispreferably a heterodimer having a non-native disulfide bond between constantdomain residues. Such display particles may be used for the creation ofdiverse TCR libraries for the identificaton of high affinity TCRs. Severalhigh affinities are disclosed.
