Soluble Universal ADCC-Enhancing Synthetic Fusion Gene and Peptide Technology and Its Use Thereof

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专利权人:

发明人:

CHIANG J. LI,SHYAM UNNIRAMAN

申请号：

US15532770

公开号：

US20170362299A1

申请日:

2015.12.08

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Novel synthetic biology-based ADCC technologies are provided that enhance or enable ADCC responses, for example, through a rationally-designed soluble universal ADCC enhancer protein (SUAEP) where a high-affinity CD3-binding domain is fused to a high-affinity Fc-binding domain. The SUAEP technology can be used to prevent or treat cancers, infectious, inflammatory or autoimmune diseases, and other diseases where elimination of diseased cells is desirable.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/