UNIVERSITE D'AIX- MARSEILLE;UNIVERSITE CLAUDE BERNARD - LYON 1;CENTRE LEON BERARD;INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE);INSTITUT JEAN PAOLI & IRENE CALMETTES
发明人:
申请号：
IL22834713
公开号：
IL228347A
申请日:
2013.09.11
申请国别(地区):
IL
年份:
2017
代理人:
摘要：
The present invention provides antibodies directed against ICOS or a derivative thereof which induce IL-10 and IFN³ production, induce CD4+ T cells proliferation, reduce Tconv proliferation, and increase the immunosuppressive function of Treg. The present invention also relates to uses of said antibodies for treating autoimmune diseases, transplantation rejection and graft versus host disease."
