GU JIJIE,HUTCHINS CHARLES W.,ZHU RONG-RONG,SHEN JIANWEI,HARRIS MARIA C.,BELANGER EILEEN,GHAYUR TARIQ,HINTON PAUL R,JUAN VERONICA M
申请号:
NZ60317909
公开号:
NZ603179A
申请日:
2009.07.08
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is a binding protein capable of binding prostaglandin E2 (PGE2), wherein the binding protein comprises an antigen binding domain containing variable heavy (VH) and variable light (VL) domains comprising framework and complementarity determining region (CDR) sequences, wherein said CDR sequences comprise: GYTFTKYWLG (SEQ ID NO: 54), DIYPGYDYTHYNEKFKD (SEQ ID NO: 55), SDGSSTY (SEQ ID NO: 56), TSSQNIVHSNGNTYLE (SEQ ID NO: 57), KVSNRFSG (SEQ ID NO: 58), and FQVSHVPYT (SEQ ID NO: 59).