The bright offer of this Hair is coated Pian System Elixirs,It includes the DPP4- inhibition Elixirs saxaglipitin or its HCl Which of the Drug object such as formula (I) of Yi Hair Inner Ringization estranged,The System Elixirs includes the label and other Chang Regulations Fu shape Elixirs that Elixirs is filled containing Yi Seed Huo Duo Seed,The label include coating on it may include Two Layer or more Layer coating,The Inner sealing coating Layer that a wherein at least Layer As You mono- Seed Huo Duo Seed coating polymer is formed,Wherein the 2nd Layer is formed by Drug object (DPP4- inhibits Elixirs) and a Seed or more Seed coating polymer,With and can Election with can not Election with but most good Election by a Seed or more Seed coating polymer formed the 3rd outside protect Nursing Layer. The method that the bright also offer of this Hair forms coating tablet with what.本發明提供包衣片製劑,其包括易發生分子內環化的藥物例如式(I)的DPP4-抑制劑saxaglipitin或其HCl鹽,該製劑包括含有一種或多種填充劑的片芯和其他常規賦形劑,該片芯包括包被在其上的可包括兩層或多層的包衣,其中至少一層為由一種或多種包衣聚合物形成的內密封包衣層,其中第二層由藥物(DPP4-抑制劑)和一種或多種包衣聚合物形成,以及可選用可不選用但最好選用的由一種或多種包衣聚合物形成的第三外保護層。本發明也提供用於形成包衣片的方法。