Akin Akinc,Alfica Sehgal,Ivanka Toudjarska,Donald Foster,Stuart Milstein,Brian Bettencourt,Martin A. Maier,Klaus Charisse,Satyanarayana Kuchimanchi,Kallanthottathil G. Rajeev,Muthiah Manoharan
申请号:
US16220157
公开号:
US20200216844A1
申请日:
2018.12.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to iRNA, e.g., double-stranded ribonucleic acid (dsRNA), compositions targeting the Serpinc1 gene, and methods of using such iRNA, e.g., dsRNA, compositions to inhibit expression of Serpinc1 and methods of treating subjects having a bleeding disorder, such as a hemophilia.