Topical and oral compositions for treating and/or preventing acne are disclosed. The compositions include effective amounts of taurine and magnesium, wherein the effective amounts are sufficient to treat and/or prevent the acne. A method for treating and/or preventing acne in a subject in need thereof is also disclosed. The method includes administering to the subject topical and/or oral compositions including taurine and magnesium in amounts sufficient to treat and/or prevent the acne.