A botanical composition for treating a patient with liver disease, e.g., Hepatitis C virus, is provided which includes dried fruit of Silybum sp., dried leaves of Cyanora sp., dried fruit of Ecballium sp., dried leaves of Centaurum sp., dried leaves of Taraxacum sp., gum of Commiphora sp., dried rhizomes of Rheum sp., dried rhizomes of Curcuma sp., dried leaves of Rosimarinus sp., dried fruit of Terminalia, sp., dried fruit of Schisandra sp., dried root of Panax sp., and dried root of Echinacea sp. The composition can be administered in any pharmaceutical dosage form suitable for enteral administration. A method for treating liver disease is provided which includes administering an effective amount of the botanical composition to a patient afflicted with liver disease. A method for manufacturing the botanical composition and unit dosage forms thereof is also provided.
