A CPAP comfort seal. The CPAP comfort seal includes a base comprising a first loop of fabric secured to a second loop of fabric, wherein the first loop of fabric and the second loop of fabric are secured to one another along a common perimeter edge. An opening is defined by an inner perimeter edge of the first loop of fabric and the second loop of fabric. An elastic band is disposed on the inner perimeter edge of the second loop of fabric. The opening is configured to receive a CPAP mask therethrough, such that elastic band contacts an outer side of the CPAP mask. The first loop of fabric contacts the wearer's face when the CPAP mask is secured thereto, providing additional sealing properties and increased comfort for the wearer.
