Anti-CD40 antibodies are formulated as lyophilisate or liquid formulation. The lyophilisates can be reconstituted to give a solution with a high concentration of the antibody active ingredient for delivery to a patient without high levels of antibody aggregation. The lyophilisate can be reconstituted with an aqueous reconstituent to provide an aqueous composition in which the antibody has a concentration of at least 50mg/ml. The lyophilisate or aqueous pharmaceutical composition may include one or more of a sugar, a buffering agent, a surfactant, and/or a free amino acid.本發明係關於經調配成凍乾物或液體調配物之抗CD40抗體。該等凍乾物可經復水以產生用於投與至患者之具有高濃度抗體活性成分而不會有高度抗體結塊之溶液。該凍乾物可利用含水復水物加以復水以產生含水組合物，其中該抗體具有至少50mg/ml之濃度。該凍乾物或含水醫藥組合物可包括一或多種糖、緩衝劑、界面活性劑及/或游離胺基酸。
