An oral hygiene instrument that includes a flossing member and a brushing member at opposite ends of an elongated handle member. An oral hygiene substance, such as xylitol, may be applied to a flossing filament of the flossing member and bristles of the brushing member. The oral hygiene instrument may include one or more coupling mechanisms at one or both of the ends of the elongated handle member to selectively engage one or both of the flossing member and the brushing member. The oral hygiene instrument may also include one or more digit placement pads that promote a positioning of an oral hygiene instrument within a users hand that is useful for flossing and brushing a users teeth. These digit placement pads may indicate a proper sequence of flossing and brushing a users teeth.