SHERR DAVID H,POLLASTRI MICHAEL,SCHLEZINGER JENNIFER,HAIGH MOLINA SARAH,SCHAUS SCOTT,GIGUERE JOSHUA ROBERT
申请号：
IN892/DELNP/2013
公开号：
IN2013DN00892A
申请日:
2013.01.29
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
Provided herein are novel agents that modulate AhR activity for use in therapeutic compositions and methods thereof for inhibiting cancer cell proliferation and tumor cell invasion and metastasis. The agents comprise AhR inhibitors or non constitutive AhR agonists of Formula (I) and (II) for the inhibition of cancer cell growth and parameters that characterize tumor metastasis such as tumor cell invasiveness.
