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D-アミノ酸ペプチド
专利权人:
イミューノメディクス、インコーポレイテッド
发明人:
ウィリアム、ジェイ.マクブライド,デイビッド、エム.ゴールデンバーグ
申请号:
JP2006533737
公开号:
JP4937751B2
申请日:
2004.06.14
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
The present invention provides compounds of the formula X-R1-D-[Dpr, Orn or Lys](A)-R2(Z)-D-[Dpr, Orn or Lys](B)-R3(Y)-NR4R5 or R1(X)-D-[Dpr, Orn or Lys](A)-R2(Z)-D-[Dpr, Orn or Lys](B)-R3(Y)-NR4R5, in which X is a hard acid cation chelator, a soft acid cation chelator or Ac-, R1, R2 and R3 are independently selected from a covalent bond or one or more D-amino acids that can be the same or different, Y is a hard acid cation chelator, a soft acid cation chelator or absent, Z is a hard acid cation chelator, a soft acid cation chelator or absent, and A and B are haptens or hard acid cation chelators and can be the same or different, and R4 and R5 are independently selected from the group consisting of hard acid cation chelators, soft acid cation chelators, enzymes, therapeutic agents, diagnostic agents and H. The present invention also provides methods of using these compounds and kits containing the compounds.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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