SHANGHAI ZHEYE BIOTECHNOLOGY LIMITED-LIABILITY COMPANY
发明人:
Jianyu Liu,Haidong Zhang
申请号:
US16474991
公开号:
US20190359610A1
申请日:
2017.12.29
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided are a compound of formula (I), a stereoisomer, a tautomer or a pharmaceutically acceptable salt thereof, use thereof as a selective inhibitor for FGFR4 kinase and use thereof in manufacturing a medicament or pharmaceutical composition for treating diseases due to FGFR4 or FGF19. The compound disclosed by the invention has selective and significant inhibitory activities against FGFR4, and has wide application prospect in the field of tumor treatment.