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A NOVEL DOSAGE FORM
专利权人:
EGALET A/S
发明人:
BAR-SHALOM, DANIEL,SLOT, LILLIAN,FISCHER, GINA,HEMMINGSEN, PERNILLE HOYRUP
申请号:
CA2566793
公开号:
CA2566793C
申请日:
2005.05.11
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
A novel dosage form. The dosage form is presented in particulate form andbefore oral ingestion the particulate material is subjected to an aqueousmedium, whereby it is converted to a semi-solid form by swelling or gelling ofone or more of the components, especially of a gellan gum, of the particulatematter. The invention also relates to a vehicle for oral administration of oneor more active substances, the vehicle comprising a gellan gum arranged in aconfiguration allowing optimal water diffusion so that upon addition of apredetermined amount of an aqueous medium, without the necessity of applyingshear forces or other mixing forces, within a time period of 5 minutes or lessswells and/or gels and the texture of the swelled vehicle being similar tothat of a soft pudding and having a viscosity of at least about 10,000 cps asmeasured by a Brookfield Viscometer with a #4 LV spindle at 6 rpm and at 20-25~C. In one embodiment of the invention, the particulate matter can bemoulded into a desired shape or pressed onto a dispensing unit such as a spoon.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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