Summary "Methyl bardoxolone 2,2-difluoropropionamide derivatives, polymorphic forms and methods of use thereof" The present invention generally relates to the compound: n - ((4as, 6ar, 6bs, 8ar, 12as, 14ar, 14bs) -11-cyano-2,2,6a, 6b, 9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a, 5,6,6a, 6b, 7,8,8a , 9,10,12a, 14,14a, 14b-octadecaidropicen-4a-yl) -2,2-difluoropropanamide, polymorphic forms thereof, methods for the preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.resumo "derivados de 2,2-difluoropropionamida de bardoxolona metil, formas polimórficas e métodos de uso dos mesmos" a presente invenção refere-se geralmente ao composto: n-((4as,6ar,6bs,8ar,12as,14ar,14bs)-11-ciano-2,2,6a,6b,9,9,12a-heptametil-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecaidropicen-4a-il)-2,2-difluoropropanamida, formas polimórficas do mesmo, métodos para a preparação e uso do mesmo, composições farmacêuticas do mes-mo, e kits e artigos de manufatura do mesmo.
