The invention relates to an anhydrous multiphase gel system consisting of anouter lipid matrix and of an inner phase gelled by means of polymer, obtainedby: a) melting the lipid phase while forming a liquid lipid phase； b) mixingand homogenizing polymers or polymer blends that are capable of swelling whileforming a polymer phase to be dispersed； combining the polymer phase with theliquid lipid phase and homogenizing the phases, and； d) cold stirring thephase mixture until forming a solid gel-like mixed structure of the entiresystem. The anhydrous multiphase gel system is particularly suited foraccommodating poorly soluble active substances in high concentrations and fortopical and transdermal applications. The described system is characterized asan EDRS Entrapped Drug Reservoir System .
