Disclosed is a cone-beam CT multi-directional scanning apparatus which comprises a host machine frame, a cone-beam CT scanning device, a scanning frame and a revolving driving device, wherein the cone-beam CT scanning device is arranged on a body of the scanning frame; and the scanning frame is connected to the host machine frame through the revolving driving device, so that the scanning frame can turn over inside the host machine frame. Scanning on a human body at a vertical position can be implemented when the scanning frame is turned to be in a lying state; and scanning on a human body's lying position can be implemented when the scanning frame is turned to be in a standing state. The cone-beam CT multi-directional scanning apparatus provided by the invention changes the current situation that three-dimensional bone imaging data on a human body's upright position cannot be acquired, and also changes the current situation that image resolving precision on a CT imaging sagittal plane is relatively low. Three-dimensional cone-beam CT imaging and two-dimensional DR forming of a patient can be implemented on the standing position and the lying position, so that three-dimensional images of human bone system and soft tissues, with high spatial precision and high density precision can be acquired.