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IMMUNOTHERAPY OF CANCER THROUGH COMBINATION OF LOCAL AND SYSTEMIC IMMUNE STIMULATION
专利权人:
IMMUNE DESIGN CORP.
发明人:
TER MEULEN, JAN, HENRIK,PAYA CUENCA, CARLOS, V.
申请号:
SG11201606625R
公开号:
SG11201606625RA
申请日:
2015.02.13
申请国别(地区):
SG
年份:
2016
代理人:
摘要:
Provided herein are compositions and methods for immunotherapy of cancers, said methods combining systemic vaccination with a recombinant expression vector encoding a viral antigen and/or a cancer specific tumor antigen(s) to induce activated CD8 T-cells, with a local (e.g., intratumoral) immune stimulation using standard or modified application of a TLR agonist, to induce local inflammatory and innate immune responses which recruit T-cells to the tumor.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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