A Magnetic Particle Imaging Device, MPI, comprising a first magnetic control system (3) configured to generate a magnetic field within a three-dimensional measurement space (4) and to obtain, within said three-dimensional space (4 ), the movement in three directions X, Y and Z of a point (5), where the field has a value lower than a threshold, also comprising said Magnetic Particle Imaging device, MPI, a second system of magnetic excitation (7) configured to generate a pulsating magnetic field within said point (5) to excite iron oxide microparticles injected into the circulatory system of a patient who has a portion of his body positioned in said three-dimensional measurement space, said control system comprises; a first lower permanent magnet (10) in the shape of a parallelepiped; a second upper permanent magnet (11) in the shape of a parallelepiped spaced apart from the first magnet in the vertical direction Z, the first permanent magnet (10) and the second permanent magnet (11) having mutually directed poles, sharing the same magnetic axes and being arranged on opposite sides of the three-dimensional measurement space (4); a first pair of first and second electromagnets (13a, 13b) arranged, respectively, opposite a first side face (15a) and a second side face (15b) of the first lower permanent magnet (10), the first and second being arranged lateral faces (15, 15b) on opposite sides of the first permanent magnet (10) in the shape of a parallelepiped, said first pair of electromagnets (13a, 13b) being configured to generate, when actuated, a magnetic field that combines with the field magnetic generated by the permanent magnets (10, 11) and modifies the spatial arrangement of the lines of force of the field along a first spatial direction X; and a second pair of third and fourth electromagnets (13c; 13d) arranged, respectively, in front of a third face (15c) and a fourth face (15d) of the first lower permanent magnet (10), the third and fourth faces being arrange