TODD, ADAM,ANDERSON, ROSALEEN JOY,SMALL, DAVID ANTONY PHILIP,GROUNDWATER, PAUL WILLIAM,BENTON, MATTHEW RICHARD
申请号：
CA2895648
公开号：
CA2895648A1
申请日:
2013.12.20
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present subject matter relates generally to compounds having the formula (I): wherein each of X, Y, R1, R2, R3, R4, and n are as defined herein. Compounds of formula (I) may act as inhibitors of the thioredoxin reductase enzyme system. The subject matter also relates to use, formulation and preparation of the compounds. The compounds may be useful in the treatment of inflammatory and oxidative diseases and conditions. The compounds may also provide useful anti-proliferative and anti- apoptotic effects.
