[PROBLEMS]To provide a compound useful as an agent for the treatment of circulatory diseases, nervous system diseases, metabolic diseases, reproductive system diseases, and digestive tract diseases.[MEANS FOR SOLVING PROBLEMS]The compound, which is for use as an active ingredient, is represented by the formula (I):[wherein R1 represents optionally halogenated C1-6 alkyl, etc. R2 represents, e.g., a group represented by the formula (II-1) or (II-4)(wherein W represents C1-6 alkylene, etc. and R represents C1-6 alkyl, etc.) R3 represents hydrogen, C1-6 alkyl, etc. X represents -O-, -NH-, etc. and Y1, Y2, Y3, and Y4 each independently represents -CH-, -N-, etc.].