PROBLEM TO BE SOLVED: To provide a pharmaceutical composition excellent in preservation stability and containing loxoprofen or its salt, and chlorpheniramine or its salt.SOLUTION: A pharmaceutical composition includes chlorpheniramine or its salt and loxoprofen or its salt so that they do not substantially come into contact with each other (provided that pharmaceutical compositions containing Loxonin (R) fine particles and Allergin (R) powder are excluded).【課題】保存安定性が優れた、ロキソプロフェン又はその塩、及びクロルフェニラミン又はその塩を含有する医薬組成物の提供。【解決手段】クロルフェニラミン又はその塩と、ロキソプロフェン又はその塩とを実質的に互いに接しないように含有する医薬組成物(但し、ロキソニン(登録商標)細粒及びアレルギン(登録商標)散を含有する医薬組成物を除く。)。【選択図】なし