The present specification discloses an adapter for coupling a blood pressure cuff to a blood pressure manifold. In one embodiment, the adapter includes an elastomeric hose having a first end and a second end and a first lumen and a second lumen. The first and second lumens define a first air pathway and a second air pathway respectively. A first end connector is integrally formed with the first end and the second end connector is integrally formed with the second end. The first end connector includes a first seal and a second seal and the second end connector includes a third seal and a fourth seal. The first end of the first lumen terminates proximate to the first seal, the second end of the first lumen terminates proximate to the third seal, the first end of the second lumen terminates proximate to the second seal, and the second end of the second lumen terminates proximate to the fourth seal. The seals are comprised of O-rings, compressible wipers, or any other equally compressible, sealing material. Optionally, for a neonate adapter, the third and fourth seals at the second end connector are replaced by an integrated single lumen tube with a neonate cuff attached at its end.