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Meningococcal conjugate vaccination
专利权人:
Novartis Vaccines and Diagnostics SRL
发明人:
Marshall, Cameron John
申请号:
AU2006205656
公开号:
AU2006205656B2
申请日:
2006.01.13
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Conjugated meningococcal capsular saccharides will be introduced into immunisation schedules in the near future, but the phenomenon of "carrier suppression" must first be addressed, particularly where multiple conjugates are to be used. In the invention, tetanus toxoid is used as the carrier protein, even where multiple meningococcal conjugates are administered at the same time and where a patient has previously been exposed to the carrier protein, either in the form of a previous immunogen (e.g. in a DTP vaccine) or as a previous carrier protein (e.g. in a Hib or pneumococcal conjugate vaccine). The invention provides a method for immunising a patient, comprising administering multiple conjugates of meningococcal capsular saccharides, wherein each conjugate comprises a tetanus toxoid carrier protein, and the capsular saccharide, and wherein the patient has been pre-immunised with a tetanus toxoid.
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