The invention relates to the field of life needs and more particularly to the field of cosmetics and/or dermatology. The invention more particularly relates to cosmetic and/or dermatological compositions having depigmentation properties, characterised in that they contain as an active ingredient a pseudoceramid having a fatty acid fraction derived from an unsaturated and mainly poly-unsaturated fatty acid. The invention also relates to the use of pseudoceramids of the general formula I as a depigmentation agent.