An object of the present invention is to provide a pharmaceutical agent or composition useful as a muscle-strengthening drug, an anti-inflammatory drug, an antiasthmatic, an antidiarrheal, an antidepressant, or a drug for the treatment of secondary diseases following cerebral infarction, motor paralysis, diminution of vision, hepatitis, inflammatory intestinal syndrome, functional enteropathy, functional cardiopathy, functional hepatopathy, functional nephropathy, dementia, climacteric symptoms, senile dementia and/or Alzheimer disease, and a dermatological agent or composition suitable for skin applications, which can treat or prevent muscle weakening and inflammation, in particular arthritis, by its muscle-strengthening and/or anti-inflammatory actions, said agent or composition comprising isoflavone and/or isoflavone glycoside in combination with a pungent substance, a bitter substance or a sour substance, and cholic acid, and/or scymnol and/or a scymnol ester. The present invention relates to an agent or composition usuful as a muscle-strengthening drug, an anti-inflammatory drug, an antiasthmatic, an antidiarrheal, an antidepressant, or a drug for the treatment of secondary diseases following cerebral infarction, motor paralysis, diminution of vision, hepatitis, inflammatory intestinal syndrome, functional enteropathy, functional cardiopathy, functional hepatopathy, functional nephropathy, dementia, climacteric symptoms, senile dementia and/or Alzheimer disease, and/or an agent or composition to be applied to the skin, said agent or composition comprising isoflavone and/or isoflavone glycoside in combination with a pungent substance, a bitter substance or a sour substance, and cholic acid, and/or scymnol and/or a scymnol ester.
