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DERIVES DE TETRAHYDROPYRANE DIRIGES CONTRE DES MALADIES NEUROLOGIQUES
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
KOLCZEWSKI, SABINE,PINARD, EMMANUEL
申请号:
CA2785776
公开号:
CA2785776C
申请日:
2011.01.28
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to a compound of general formula (I) wherein X is -O- or -CH2-; X' is -O- or -CH2-; with the proviso that one of X or X' is always -O- and the other is -CH2-.It has been found that the compounds of general formula (I) are good inhibitors of the glycine transporter 1 (GIyT-1) and therefore they may be used for the treatment of schizophrenia, psychoses and other neurological conditions, including pain.
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