The syringe has a barrel stopper (12) movable in a syringe cylinder (1) by a piston rod (11), and a needle assembly (25) accommodated in the cylinder. The rod and the assembly are connected by a coupling unit (20) to draw the assembly back into the cylinder after injection is completed. The assembly has a plastic needle holder (26) that encloses a stainless steel injection needle (27). The holder receives an injection solution (50) in relation to the interior of the cylinder. The holder is sealed off by a pharmaceutical rubber sealing insert (36), by which the rear end of the needle protrudes.