Johannes Petrus Jozef Maria De Munter,Ekkehard Lang,Erik Charles Marie Joseph Wolters,Petrus Theodorus De Haan
申请号:
US15029206
公开号:
US20160228468A1
申请日:
2014.10.24
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The disclosure is in the field of cell therapy, more in particular, stem cell transplantation therapy. The disclosure provides methods and compositions for improving the efficacy of stem cell transplantation therapy by reducing the inflammatory activity of a stem cell transplant. More in particular, the disclosure provides a method for preparing a stem cell transplant with reduced inflammatory activity comprising a step of suspending a composition comprising stem cells in a fibrinogen-depleted plasma and/or in a fibrinogen and C-reactive protein-depleted plasma.