A system and method for enhancing the determination of the blood pressure of a patient is disclosed. The system includes a wireless blood pressure sensing device that obtains blood pressure data from the patient and wirelessly transmits the data to a host system. The host system receives at least one other physiological parameter from the patient and can retrieve historical information about the patient. Based upon the blood pressure data, physiological parameter and historic data, the host system utilizes a multi-parameter algorithm to calculate a remote blood pressure reading. The blood pressure sensing device calculates a local blood pressure reading based upon the obtained blood pressure data. The host system communicates with the blood pressure sensing device to modify operation of the blood pressure sensing device based upon the at least one physiological parameter other than blood pressure, the historic patient information as well as the calculated remote reading.
