A catheter is provided that includes first and second balloons on a catheter shaft. The first balloon includes a cylindrical main section extending between first and second ends thereof defining a first interior communicating with an inflation lumen of the catheter shaft, and a second balloon including a first end attached to the catheter shaft adjacent the first end of the first balloon and a second end extending over the main section of the first balloon such that the second balloon defines a second interior. The first balloon includes openings in the membrane of the first balloon that are located within the second interior to allow inflation media delivered through the inflation lumen to enter the first interior to inflate the first balloon and pass through the one or more openings into the second interior to inflate the second balloon sequentially or simultaneously with the first balloon.