FORMULE AQUEUSE STABLE AMELIOREE DE (E)-4-CARBOXYSTYRYL-4-CHLOROBENZYL SULFONE

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专利权人:

INC.;ONCONOVA THERAPEUTICS

发明人:

MANIAR, MANOJ

申请号：

CA2792913

公开号：

CA2792913C

申请日:

2011.03.24

申请国别(地区):

CA

年份:

2020

代理人:

摘要：

An aqueous pharmaceutical solution com-position comprising between about 20 mg/ml to about 100mg/ml of a radioprotective .alpha.,.beta.-unsaturated aryl sulfone, acosolvent comprising polyethylene glycol (PEG),polypropylene glycol, polyglycerol, DMA, propylene glycol,glycerol, ethanol, sorbitol, isopropyl alcohol, or acombination thereof in an amount between about 25% andabout 90% w/v, and a water soluble Vitamin E derivative,wherein the composition has a pH within the range ofabout 7.0 to about 9.5.

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