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Stable MIA/CD-RAP formulation
专利权人:
Scil Technology GmbH
发明人:
Klaus Hellerbrand,Rainer Sigl
申请号:
US13661743
公开号:
US09511116B2
申请日:
2012.10.26
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to stable aqueous formulations comprising at least 5 mg/mL CD-RAP and a charged amino acid, said amino acid preferably having a net charge at a pH between about 6 and 8. The ingredients of the formulation preferably provide stability over repeated freeze-thaw cycles. In a preferred aspect, the formulation is for use in therapy, preferably for use in the treatment of inflammatory disorders, preferably osteoarthritis. Furthermore, a kit comprising the formulation of the invention is provided.
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