Ekambar R. Kandimalla,Tao Lan,Yukui Li,Dong Yu,Daqing Wang,Mallikarjuna Reddy Putta,Sudhir Agrawal
申请号：
US13353905
公开号：
US08759310B2
申请日:
2012.01.19
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention relates to the therapeutic use of stabilized oligoribonucleotides as immune modulatory agents for immune therapy applications. Specifically, the invention provides RNA based oligoribonucleotides with improved nuclease and RNase stability and that have immune modulatory activity through TLR7 and/or TLR8.
