Celia Lafuente Blanco;Ana Belen Benito Collado;Maria Angeles Martinez-Grau;Miguel Angel Toledo Escribano;Concepcion Pedregal Tercero;Alma Maria Jimenez-Aguado;Nuria Diaz Buezo
发明人:
Ana Belen Benito Collado,Nuria Diaz Buezo,Alma Maria Jimenez-Aguado,Celia Lafuente Blanco,Maria Angeles Martinez-Grau,Concepcion Pedregal Tercero,Miguel Angel Toledo Escribano
申请号:
US13504176
公开号:
US20120214784A1
申请日:
2010.11.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
An ORL-1 receptor antagonist of the formula: its uses, and methods for its preparation are described. ORL-1 antagonists are deemed to be useful in the treatment of depression and/or the treatment of overweight, obesity, and/or weight maintenance post treatment for overweight or obesity. Certain compounds have also demonstrated through animal models that the compounds of the present invention are useful for the treatment of migraines.