RAYKOV, ZAHARI,ROMMELAERE, JEAN,GIESE, NATHALIA,APRAHAMIAN, MARC
申请号：
CA2710889
公开号：
CA2710889C
申请日:
2008.12.19
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
A parvovirus characterized by a CpG-enriched genome, wherein the genomecontains at least 2 additional CpGinserts that are not present in the wild type genome is described as well asthe use of said parvovirus, e.g., a parvovirus based onparvovirus H1, LuIII, Mouse minute virus (MMV), Mouse parvovirus (MPV), Ratminute virus (RMV), Rat parvovirus (RPV),Rat virus (RV), vectors based on the foregoing viral species, and/or cellscapable of actively producing the foregoing viral speciesfor the preparation of a pharmaceutical composition, e.g., for the treatmentof cancer, preferably pancreas carcinoma, hepatoma orlymphoma.
