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MATÉRIAU ANTITHROMBOTIQUE
专利权人:
Toray Industries; Inc.
发明人:
申请号:
EP16800111.3
公开号:
EP3305342A4
申请日:
2016.05.27
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention aims to provide an antithrombogenic material which has a reduced thickness of its coating material, and which maintains high antithrombogenicity for a long period. The present invention provides an antithrombogenic material comprising: a coating material containing: a cationic polymer containing, as a constituent monomer, a compound selected from the group consisting of alkyleneimines, vinylamines, allylamines, lysine, protamine, and diallyldimethylammonium chloride; and an anionic compound containing a sulfur atom and having anticoagulant activity; and a base material whose surface is coated with the coating material; wherein the cationic polymer is covalently bound to the base material; the anionic compound containing a sulfur atom and having anticoagulant activity is immobilized on the surface of the base material by ionic bonding to the cationic polymer; and the average thickness of the coating material is 15 to 400 nm.
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