FERRER MONTIEL, Antonio Vicente,FERNANDEZ CARVAJAL, Asia,BELMONTE MARTINEZ, Carlos,GALLAR MARTINEZ, Juana,DE LA TORRE, Roberto,GENAZZANI, Armando,TRON, Gian Cesare,MERCALLI, Valentina
申请号：
EP17741136
公开号：
EP3406600A4
申请日:
2017.01.17
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The invention relates to compounds having formula (I) wherein A is selected from the group consisting of: a) optionally substituted (C 1 -C 8 ) alkyl； b) optionally substituted (C 3 -C 6 ) cycloalkyl； c) optionally substituted (C 6 -C 14 ) aryl； d) optionally substituted (C 6 -C 14 ) heteroaryl； e) C(0)-(C 6 -C 14 ) aryl, in which group (C 6 -C 14 ) aryl is optionally substituted； f) C(0)-(C 6 -C 14 ) heteroaryl, in which group (C 6 -C 14 ) heteroaryl is optionally substituted； g) CH(OH)-(C 6 -C 14 ) aryl, in which group (C 6 -C 14 ) aryl is optionally substituted； and h) CH(OH)-(C 6 -C 14 ) heteroaryl, in which group (C 6 -C 14 ) heteroaryl is optionally substituted. The invention also relates to methods for the production of said compounds, to pharmaceutical and veterinary compositions comprising said compounds and to the therapeutic uses thereof, such as for the prevention and/or treatment of dry eye syndrome, vaginal dryness and/or burning mouth syndrome.
