DERIVES DE N-(HETERO)ARYL-PYRROLIDINE DE PYRAZOL-4-YL-PYRROLO[2,3-D]PYRIMIDINES ET PYRROL-3-YL-PYRROLO[2,3-D]PYRIMIDINES EN TANT QU'INHIBITEURS DE LA JANUS KINASE
RODGERS, JAMES D.,SHEPARD, STACEY,ARVANITIS, ARGYRIOS G.,WANG, HAISHENG,STORACE, LOUIS,FOLMER, BEVERLY,SHAO, LIXIN,ZHU, WENYU,GLENN, JOSEPH P.
申请号：
CA2762174
公开号：
CA2762174C
申请日:
2010.05.21
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to N-(hetero)aryl-pyrrolidine derivatives ofFormula (I): which are JAK inhibitors,such as selective JAK1 inhibitors, useful in the treatment of JAK-associateddiseases including, for example, inflammatory andautoimmune disorders, as well as cancer.
