Anncatrine Luisa Petersen,Palle Hedengran Rasmussen,Jonas Rosager Henriksen,Andreas Kjær,Thomas Lars Andresen
申请号:
US13383310
公开号:
US20120213698A1
申请日:
2010.07.16
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to a novel composition and method for loading delivery systems such as liposome compositions with radionuclides useful in targeted diagnostic and/or therapy of target site, such as cancerous tissue and, in general, pathological conditions associated with leaky blood vessels. The composition and methods of the invention find particular use in diagnosing and imaging cancerous tissue and, in general, pathological conditions associated with leaky blood vessels in a subject. The present invention provides a new diagnostic tool for the utilization of positron emission tomography (PET) imaging technique. One specific aspect of the invention is directed to a method of producing nanoparticles with desired targeting properties for diagnostic and/or radio-therapeutic applications.