Substituted quinazolin-4-ones for inhibiting ubiquitin specific protease 7

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专利权人:

Frédéric Colland;Marie-Edith Gourdel

发明人:

Frédéric Colland,Marie-Edith Gourdel

申请号：

US14241923

公开号：

US09546150B2

申请日:

2012.08.29

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The present invention relates to quinazolin-4-one compounds of formula (I′), their process of preparation and uses thereof. These compounds are useful as selective and reversible inhibitors of ubiquitin specific proteases, particularly USP7, for treating e.g. cancer, neurodegenerative diseases, inflammatory disorders and viral infections.

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