A device and method for collecting a urine sample from a neonate is provided. The device is attached to the neonate shortly after birth and removed after the neonate produces a urine sample. An interior shell and an exterior shell form the device, and an absorbent material is located inside the interior shell to absorb the urine sample. The interior shell and the exterior shell are connected by a hinge and are initially in a nesting position, with the exterior shell on top of the interior shell. After the urine sample is absorbed by the absorbent material, the exterior shell is rotated around an axis defined by the hinge to contact and compress the absorbent material to release the urine sample for collection.
