Crystalline Forms I and II of (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate and compositions, methods of manufacture and therapeutic uses thereof are described.Linvention concerne les formes cristallines I et II de monohydrate dhydrochlorure de (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide, des compositions, des procédés de production et leurs utilisations thérapeutiques.