Disclosed herein is a new crystal form VII of agomelatine, the preparation method and use thereof and a pharmaceutical composition containing the same. Also disclosed is the method for the preparation of crystal form VII of agomelatine, which comprises dissolving form II or III agomelatine compounds in acetic acid, to which potassium acetate or ammonium acetate is then added, followed by the addition of water dropwise to this reaction mixture, which is then agitated at a temperature of 17-23°C in order to bring about crystallization, and the crystals are then separated from the solution. The new crystal form has a good purity, a stable crystal form and good reproducibility； the preparation method thereof is easy to amplify； and it is superior to most previously reported crystal forms in terms of stability and solubility.
