An orthosis, in particular an orthopedic post-operative knee brace, consists of a base comprising a central mesh zone (33), a pair of zones (31, 32) with a three-dimensional development, inserts (34, 35) fixed to said base and comprising slots (36, 37) for straps to pass through, and covers for any joints, in addition to blocking inserts (38, 39) at the respective right and left ends of the knee brace, designed to engage together to adapt and block the knee brace (30) to the leg of a patient at the knee.Said base consists of a single seam-free piece obtained by means of an electronic flat-bed knitting machine, in which said central zone (33) is a mesh and said zones (31, 32) with a three-dimensional development are connected uninterruptedly to said central zone (33).Other types of orthoses, in particular jackets, ankle braces, wrist braces and elbow braces, can be produced following the same principles.
