John Telford;Guido Grandi;Immaculada Margarit Y Ros;Cira Daniela Rinaudo;Domenico Maione
发明人:
John Telford,Guido Grandi,Immaculada Margarit Y Ros,Cira Daniela Rinaudo,Domenico Maione
申请号：
US12906510
公开号：
US08778358B2
申请日:
2010.10.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B Streptococcus serotypes and isolates. The adhesin islands are thought to encode surface proteins which are important in the bacteria's virulence. Thus, the adhesin island proteins of the invention may be used in immunogenic compositions for prophylactic or therapeutic immunization against GAS or GBS infection. For example, the invention may include an immunogenic composition comprising one or more of the discovered adhesin island proteins.
