Jung Ju Kim,Su Hyun Jung,Hyun Seung Ryu,Jun Hyuk Seo
申请号:
US15401455
公开号:
US09925306B2
申请日:
2017.01.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a carrier for growth factor related to regeneration of bone tissues that is capable of arbitrarily controlling the delivery rate of growth factors related to bone regeneration and thus especially applicable to a bone void filler in the fields of the dental or orthopedic applications.The carrier for controlling the delivery rate of the growth factor in the present invention is composed of a hyaluronic acid hydrogel having a distribution of interconnected pores and a calcium phosphate microsphere being distributed in the pores of the hyaluronic acid hydrogel. The calcium phosphate microsphere having a porosity suitable for delivery of the growth factor is positioned into the pores of the cross-linked hyaluronic acid hydrogel to complete the carrier.