您的位置: 首页 > 农业专利 > 详情页

Reactive oxygen species production by myeloid-derived suppressor cells as a predictor of patient response to interferon-α therapy
专利权人:
UNIVERSITY OF PITTSBURGH—;OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
发明人:
Larisa Geskin,Oleg E. Akilov
申请号:
US15485420
公开号:
US10627403B2
申请日:
2017.04.12
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to methods and materials for more effectively treating patients with interferon. It is based on the discovery that clinical response to interferon (IFN) therapy is mediated in part by inhibition of activation of MDSC and such inhibition can be observed after a test dose of interferon; a significant decrease of reactive oxygen species (ROS) production by MDSC (as a measure of their activation) after IFN therapy is predictive of overall response to immunotherapy in cancer patients.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充